COSMOSIL<sup>®</sup> 5C18AR-II


The majority of chromatographers use reversed phase silica-based HPLC columns due to their excellent retention characteristics, high theoretical plate number, good cost-performance and ease of use. C18 or ODS reversed phase columns are the most general and popular types. Monomeric and polymeric types are available differing considerably in their retention characteristics.
Nacalai has been offering the monomeric type COSMOSIL® 5C18-MS and the polymeric type COSMOSIL® 5C18-AR columns, both well received by many chromatographers due to their excellent performance. However, the COSMOSIL® 5C18-AR-II can be used for a wider range of compounds than other polymeric types of columns already in use.

Material characteristics
COSMOSIL® 5C18- AR-II
Silica gel high purity porous spherical silica
Average particle size 5µm
Average pore size approx. 120Å
Specific surface area approx. 300m2/g
Stationary phase polymeric octadecyl group
End capping treatment near-perfect treatment
Carbon content approx. 17%


Characteristics

The COSMOSIL® 5C18-AR-II packed column features a polymeric and near-perfectly end capped type of C18 reversed phase material that employs an ultra-pure silica gel low in metal impurities. In addition, it has stronger acid resistance than the COSMOSIL® 5C18-AR. The COSMOSIL® 5C18-AR-II column is especially effective for the separation of chelating compounds as well as both acidic and basic compounds.
This series of columns is also highly recommended for a wide range of applications particularly in situations where monomeric-type column (for instance, COSMOSIL® 5C18-MS-II) is not as effective as expected.

Acid resistance

The acid resistance of COSMOSIL® 5C18-AR-II is much improved compared with 5C18-AR. It retains high performance even in case of acidic mobile phase used to separate proteins and peptides.
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COSMOSIL MS-II / AR-II / PAQ (PDF file)


Ordering information

Product name Size Code No. End-fitting
COSMOSIL® 5C18-AR-IIGuard Column 4.6mmI.D.x 10mm 38141-61 Waters type
4.6mmI.D.x 10mm
Cartridge (contains 3 guard)
38008-89
10.0mmI.D.x 20mm 38148-91
20.0mmI.D.x 20mm 34458-51
20.0mmI.D.x 50mm 34479-81
28.0mmI.D.x 50mm 34363-81
COSMOSIL® 5C18-AR-IIPacked Column 1.0mmI.D.×50mm 02955-21
1.0mmI.D.×150mm 02951-61
2.0mmI.D.×30mm 05098-71
2.0mmI.D.×50mm 34400-81
2.0mmI.D.×100mm 34469-11
2.0mmI.D.×150mm 37992-51
2.0mmI.D.×250mm 05272-71
3.0mmI.D.×100mm 05791-71
3.0mmI.D.×150mm 38028-61
3.0mmI.D.×250mm 38029-51
4.6mmI.D.x 30mm 05877-61
4.6mmI.D.x 50mm 38142-51
4.6mmI.D.x 100mm 38143-41
4.6mmI.D.x 150mm 38144-31
4.6mmI.D.x 250mm 38145-21
6.0mmI.D.x 150mm 38146-11
6.0mmI.D.x 250mm 38147-01
10.0mmI.D.x 50mm 05369-21
10.0mmI.D.x 150mm 34350-41
10.0mmI.D.x 250mm 38149-81
20.0mmI.D.x 150mm 34316-01
20.0mmI.D.x 250mm 38150-41
28.0mmI.D.x 250mm 34362-91



 
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