This column is based on an ultra-pure silica gel (more than 99.99%) with carbon content of only 8.5%. Therefore the retention of polar compounds is relatively longer than that on the C18-MS-II or C18-AR-II. This column is also suitable for the analysis of a wide range of chemical compounds including polypeptides.
Material characteristics
COSMOSIL® 5C18-P-MS Silica gel high purity porous spherical silica Average particle size 5µm Average pore size approx. 120Å Specific surface area approx. 300m²/g Stationary phase monomeric type octadecyl group End capping treatment near-perfect treatment Carbon content approx. 8.5%
Comparison data using different COSMOSIL® C18 columns
The COSMOSIL® 5C18-P-MS gives quicker separation of most samples compared with other COSMOSIL® 5C18 type columns. However, there is a characteristic by which the polar compounds are retained relatively longer on the COSMOSIL® 5C18-P-MS.
Separation of di-substituted benzene isomers
Because their characteristics (eg. polarity) and structure is very similar, isomers of di-substituted benzene are one of the most difficult samples to separate. It is possible to separate them at a high probability by using either any or a combination of three types of COSMOSIL® C18 (MS-II, AR-II, P-MS). ClickClick
Ordering information
Product name Size Code No. End-fitting COSMOSIL® 5C18-P-MS Guard Column 4.6mmI.D.x 10mm 34257-81 Waters type COSMOSIL® 5C18-P-MS Packed Column 4.6mmI.D.x 150mm 37995-21 4.6mmI.D.x 250mm 37994-31
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