COSMOSIL<sup>®</sup> SL-II-PREP

COSMOSIL® SL-II-PREP is an extremely high performance packing material for preparation with similar characteristic to the 5SL-II for normal phase chromatography. In SL-II-PREP the high purity silicagel raw material is treated during the process to achieve ultra purity. This way SL-II-PREP excellently separates compounds with carbonyl, phenolic or hydroxy groups,- a task used to be very difficult so far. We highly recommend the use of the SL-II series for preparation after HPLC analysis with 5SL-II.
*All chromatograms shown below are obtained with silicagel packed into stainless steel columns.


Material characteristics


75SL-II-PREP 140SL-II-PREP
Silica gel high purity porous spherical silica
Average particle size 75µm 140µm
Average pore size approx.120Å
Specific surface area approx.300m2/g
Application open column chromatography, flash column chromatography


Influence of particle size on peak the shape

The SL-II-PREP is available in three sizes: 5 and 75, 140µm (particle diameter). The sharpness of the peak is different depending on the particle size. However, the elution behavior remains the same.

Click Click

Ordering information

Product name Packing Size Code No.
COSMOSIL® 75SL-II-PREP 100g 38012-64
500g 38012-35
1kg 38012-51
COSMOSIL® 140SL-II-PREP 100g 38013-54
500g 38013-25
1kg 38013-41




(C)2004 Nacalai Tesque, Inc. E-mail: info.intl@nacalai.co.jp