Injection of samples containing particulates (microparticles, precipitates, colloid substances) will clog HPLC columns, shorten injector life, and result in extensive maintenance on pumps. Cosmonice filters are used to remove particulates from samples and prolong the life of HPLC system components. There are two types of Cosmonice filters as stated below.

W series (Aqueous solution)

W series are installed with low adsorption hydrophilic durapore filter (polyvinylidenedifluoride, PVDF). W series can be used with both aqueous and organic solvents. They are best suited for prefiltration of protein and other biological samples.

S series (Organic solvents)

S series are installed Teflon filter (polytetrafluoroethylene, PTFE) with strong resistance to organic solvents, acids and alkalis. They are best suited for prefiltration of samples with aggressive organic solvents such as chloroform and tetrahydrofuran.

Brochures

• Cosmonice Filter/Cosmospin Filter (1.2 MB)

Ordering information

Product Name	Pore size	Process volume	Hold-up volume	Connection	Product No.	PKG size
Cosmonice Filter W (Aqueous) 4 mm	0.45 µm	less than 1 ml	< 10 µl	Inlet: luer-lock Outlet: luer-dlip Connectable needles	06543-04	100 pkg
13 mm	0.45 µm	0.5-10 ml	< 30 µl		06544-94	100 pkg
Cosmonice Filter W (Aqueous) 25 mm	0.45 µm	3-50 ml	< 100 µl		06545-84	50 pkg
Cosmonice Filter S (Solvent) 4 mm	0.45 µm	less than 1 ml	< 10 µl		06541-24	100 pkg
Cosmonice Filter S (Solvent) 13 mm	0.45 µm	0.5-10 ml	< 30 µl		06542-14	100 pkg

(Storage) RT: Room temperature, A: Cool and dark, R: Refrigerator, F: Freeze

Cosmospin filters are used to remove fine particles and precipitates from samples by centrifugation. They utilize Omnipore hydrophilic PTFE membrane filter, which has a wide range of chemical resistance. Cosmospin filters are the best choice for HPLC sample filtration. Two pore sizes, G (0.2 µm) and H (0.45 µm), are available.

Ordering information

Product Name	Pore size	Maximum sample volumn	Hold-up volume	Maximum Centrifuge force	Rotor size (fixed-angle)	Filtration area	Color	Product No.	PKG size
Cosmospin Filter G	0.2 µm	0.4 ml	5 µl	5,000 x g	1.5 ml	0.2 cm2	brown	06549-44	100 pkg
Cosmospin Filter H	0.45 µm	0.4 ml	5 µl	5,000 x g	1.5 ml	0.2 cm2	white	06540-34	100 pkg

(Storage) RT: Room temperature, A: Cool and dark, R: Refrigerator, F: Freeze

Dimention: Diameter 10.6 mm x Length 45 mm
Membrane: Omnipore Hydrophilic PTFE
Sample reservoir and collection tube: Polypropylene

Chemical compatibility

Solvent	Cosmonice W series	Cosmonice S series	Cosmospin
Acetic Acid, 98%	+	+	+
Acetone	-	+	+
Acetonitrile	+	+	+
Ammonia Solution (6N)	+	+	+
Ammonium Hydroxide (Conc.)	+	+	-
Amyl Alcohol	+	+	+
Benzene	+	+	+
Benzyl Alcohol	+	+	+ (1%)
Boric Acid	+	+	+
Butyl Acetate		+
Carbon Tetrachloride	+	+	+
Chloroform	+	+	+
Cyclohexanone	-	+	+
Dichloromethane
Diethylacetamide	-	+	+
Dimethyl sulfoxide (DMSO)	-	+	+
Dimethylformamide	-	+	+
Dioxane	+	+	+
Ethers	+	+	+
2-Ethoxyethanol	+	+
Ethyl Acetate	+	+	+
Ethyl Alcohol	+	+	+
Ethylene Glycol	+	+	+
Formamide
Freon, TF or PCA Solvent	+	+	+
Gasoline	+	+	+
Glycerine (Glycerol)	+	+	+
Helium Gas	+	+
Hexane	+	+	+
Hydraulic Oil (5606)
Hydrochloric Acid (6N)	+	+	+
Hydrofluoric Acid	+	+	-
Hydrogen Gas	+	+	+
Hydrogen Peroxide (3%)	+	+	+
Isopropyl Acetate	+	+	+
Isopropyl Alcohol	+	+	+
Kerosene	+	+	+
Methanol	+	+	+
Methyl Ethyl Ketone	+	+	+
Methyl Isobutyl Ketone	+	+	+
2-Methyl-1-Propanol	+	+	+
Nitric Acid (6N)	-
Nitrobenzene	+	+	+
Ozone Gas	-	+	-
Paraldehyde	+	+	+
Pentane	+	+	+
Petroleum Ether	+	+
Phenol (Water Saturated)	+	+	+
Phosphate Buffer Solution
2-Propanol	+	+	+
Pyridine	-	+	+
Seawater	+	+	+
Silicone Oils	+	+	+
Sodium Hydroxide (Conc.)	-	-	-
Sodium Thiosulfate (Photo Fixing Solution)			+
Sulfuric Acid (6N)	+	+	+
Tetrahydrofuran (THF)	+	+
Toluene	+	+	+
Trichloroacetic Acid	+	+
Trichloroethane	+	+	+
Trichloroethylene	+	+	+
Trifluoroacetic acid (TFA)	+	+
Xylene	+	+	+

++: Recommended, --: Not recommended, (brank): No data

Brochures

• Cosmonice Filter/Cosmospin Filter (1.2 MB)