Saccharides are not retained on standard C18 columns because of their low hydrophobicity. COSMOSIL Sugar-D and NH2-MS are specifi cally designed for separation of saccharides. COSMOSIL C18-PAQ is recommended for hydrophobic glycosides or saccharide derivatives.

Specifications

Packing Material	Sugar-D	NH2-MS
USP Code		L8
Silica Gel	High Purity Porous Spherical Silica
Average Particle Size	5 µm
Average Pore Size	-	approx. 120Å
Specific Surface Area	-	approx. 300 m2/g
Bonded Phase Stracture	-
Stationary Phase	Secondary/tertiary amine	Aminopropyl group
Bonding Type		Polymeric
Target Substances	Monosaccharides, oligosaccharides
End Capping Treatment		Near-perfect Treatment
Carbon Content	-	approx. 4%
Feature	First choice for saccharide analysis High durability Good quantitative analysis	Different selectivity from Sugar-D

Comparison of Retention

The conventional aminopropyl column is slightly more retentive than Sugar-D. The retention time can be adjusted by increasing the concentration of acetonitrile in the mobile phase by 5%-10% as shown below.

Condition
Column Size	4.6 mm I.D. x 250 mm	Detection	RI
Flow Rate	1.0 ml/min	Sample	D-(+)-Glucose Maltose
Temperature	30°C